Biological parameter change of myopic eyes

Abstract

Objective A research of biological parameter of myopic eyes. Methods One hunderd amd ten human subjects (one hunderd and seventy-four eyes) were included in this re- search. Retinoscopy was made to measure refractive errors, corneal topographer was measured by corneal to- pography system, Tonometry was used to measure IOP, Ultrasonagraphy was applied to measure anterior cham- ber length,len thickness and vitreous length respectively,Laser interference biometer was used to measure axial length, Optical coherence tomography was used to measure retina thickness of fovea area. Based on spherical e- quivalent subjects were divided into four groups: emmetropia group(SE<-0.50D), low-myopia group(-0.50D≤ SE<-3.00D), moderate myopia group ( -3.00D≤ SE<-6.00D )and high myopia group ( SE≥-6.00D ). compare biological parameter with each other in different groups,and analysis the correlation between the spherical e- quivalent and other biological parameters.Results Refraction results in emmetropia group,low-myopi a group, moderate myopia group and high myopia group were -0.07±0.14 (D),-2.10±0.57 (D), -4.53±0.78 (D), -7.73±1.34 (D)respectively ,there was significant difference between each other (P <0.001 ). the anterior chamber lengths in emmetropia myopia group was less than moderate myopia group and high myopia group. there was no significant difference of other biological parameter between each group.Conclusion anterior chamber lengths in some degrees increases with SE, and vitreous length and axial length increases with SE of linear tendency, there were no obvious changes of others parameters with increases of SE.The increase of vitre- ous length attrubites to the increase of axial length and values of SE. Key words: Myopia; Biological parameter; Change