Abstract
Objective To explore the biological motion perception in Parkinson’s disease (PD). Methods 45 individuals with idiopathic PD were compared with 45 matched healthy controls (HCs) using a duration discrimination task. Results The point of subjective equality(PSE) was negative value (-0.27±0.17) for health controls (HCs), and there was significant difference compared with PSE=0 by one sample t test (t=10.96, P<0.01). Compared with HCs, the PSE for PD patients (-0.14±0.30) significantly decreased (t=2.63, P=0.01). When further dividing PD into early stages (stage 1-2) and late stages (stage 3-4), significant difference was found between late-stage PD patients(0.02±0.39)and HCs (t=4.07, P=0.008), but not between early-stage PD patients(-0.24±0.14)and HCs(t=0.84, P=0.405). Conclusion There is biological motion perception disorder in PD patients and it is related to the severity of PD. Key words: Parkinson’s disease; Biological motion; Cognition; Mirror neuron system
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