Abstract

Artificial immune systems (AISs) to date have generally been inspired by naive biological metaphors. This has limited the effectiveness of these systems. In this position paper two ways in which AISs could be made more biologically realistic are discussed. We propose that AISs should draw their inspiration from organisms which possess only innate immune systems, and that AISs should employ systemic models of the immune system to structure their overall design. An outline of plant and invertebrate immune systems is presented, and a number of contemporary systemic models are reviewed. The implications for interdisciplinary research that more biologically-realistic AISs could have is also discussed.

Highlights

  • The field of Artificial Immune Systems began in the early 1990s with a number of independent groups conducting research which used the biological immune system as inspiration for solutions to problems in non-biological domains

  • In this position paper we focus on biological metaphors and discuss the areas of biology that we believe should be important in inspiring future Artificial immune systems (AISs)

  • In this paper we have argued for the need for AISs which are based on much more biologically-realistic models

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Summary

Introduction

The field of Artificial Immune Systems began in the early 1990s with a number of independent groups conducting research which used the biological immune system as inspiration for solutions to problems in non-biological domains. We concur with Timmis [2] that this is due to a limited application to challenging problems, a lack of theoretical advances, and the use of naive biological metaphors In this position paper we focus on biological metaphors and discuss the areas of biology that we believe should be important in inspiring future AISs. Our intention is to draw the attention of AIS researchers to these areas and to provide references to key papers which we have found useful in understanding the biology. As a survey of past ICARIS proceedings [4] reveals, the majority of AISs built so far have been built for the purpose of discriminating self from nonself This is not just arguing over semantics, but goes to the heart of the engineering philosophy used to build AISs. Even if we must build AISs which incorporate adaptive immune system mechanisms, it makes little sense to build them based only the adaptive immune system. The paper ends with a brief discussion of the implications for interdisciplinary research that more biologically-realistic AISs could have

Non-human immune systems
Plant immune systems
Vertebrate and invertebrate immune systems
Systemic models of the human immune system
Infection and danger
Maintenance and homeostasis
Conclusion
Findings
23. HMS Beagle: The Great Debate

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