Biological function of endoecology (cleanliness of intercellular environment) realize two biolocical reactions: excretion reaction and inflammation reaction - utilization in vivo, in situ catabolites of the large molecular mass.

Abstract

For the biological functions of trophology (nutrition) and homeostasis, we believe that the third place is occupied by the function of endoecology: in a single pool of intercellular environment in vivo it must be "pure". The biological function of endoecology, realizes two biological reactions: the reaction of excretion and the reaction of inflammation. The biological reaction of excretion is the filtration of phlogogens of a small mol. mass through the basement membrane of the glomerulus of the nephron and excretion with the final urine. Flogogens are a great mol. mass (more than 70 kDa), catabolites of biological reactions of apoptosis, autophagy must be disposed of in situ, on site. At the stages of phylogenesis, the cells formed structures for the collection and utilization of phlogogens of large mol. mass and exogenous pathogens in tissues. The sequence of biochemical reactions, biological methods of in vivo collection and in situ utilization of phlogogens of large mol. mass and realizes the biological function of endoecology, the biological reaction of inflammation. It functions constantly, every minute, like the biological reaction of excretion. Inflammation is the reaction of maintaining the "cleanliness" of the "piece" of the ocean that every individual has privatized, before beginning to live on land. The inflammation reaction includes congenital, acquired immunity, humoral mediator systems, cytokines and eicosanoids. In the formation of a closed circulatory system, the pool for collecting and utilizing in situ biological catabolites from the bloodstream is located in the late phylogeny of the intima of the arteries of the elastic (muscular-elastic) type. Abuse of herbivorous species Homo sapiens carnivorous (meat) food; blockade of cellular absorption by polyene fatty acids in low density lipoproteins and the absence of acidic hydrolase expression of polyene fatty acids - cholesterol alcohol ethers in monocytes and macrophages - is the cause of the formation of atheroma of intima of the arteries of the elastic type. Atherosclerosis - the pathology of the biological function of trophology, atheromatosis - pathology of the biological function of endoecology. The appointment of patients statins for primary prevention of atherosclerosis, atheromatosis and coronary heart disease, we finally "passed".