Abstract
Objective: The purpose of this study was to analyze the relationship between biological factors with distress of diabetes type 2.Material and Methods: The research method is quantitative correlation. Samples were taken by accidental sampling method for 3 months (November 2017-January 2018) in 44 patients who were treated at PKU Muhammadiyah Yogyakarta Hospital and PKU Muhammadiyah Bantul Hospital in Yogyakarta, Indonesia. The instruments of the study were medical records, diabetes distress scale (DDS17) questionnaire, sphygmomanometer, scales, and microtoise. Data analysis used was ordinal logistic regression.Result and Discussion: The results of the study showed 70.5% respondents were hyperglycemic; 79.5% respondents had normal total cholesterol; 45.5% respondents had normal HDL cholesterol; 52.3% respondents had normal LDL cholesterol; 63.6% respondents had normal triglycerides; 68.2% respondents had a normal BMI; 63.6% respondents had comorbidities; 50.0% respondents had complications; 72.7% respondents suffer from hypertension; and 68.2% respondents suffer from DM> 5 years. The result also showed 50.0% respondents had mild distress; 43.2% respondents had moderate distress; and 6.8% had severe distress.Conclusion: It was concluded that biological factors related to distress were comorbidities, complications, BMI and total cholesterol.International Journal of Human and Health Sciences Vol. 03 No. 04 October’19 Page : 207-217
Highlights
The prevalence of diabetes in the world is increasing
The emergence of insulin resistance in the elderly can be caused by four factors, namely: (1) less muscle mass and more fat tissue; (2) decreased physical activity resulting in a decrease in the number of insulin receptors that were ready to bind to insulin; (3) dietary changes, namely eating more carbohydrates due to reduced number of teeth; (4) neurohormonal changes especially plasma insulin-like growth factor-1 (IGF-1) and dehidroepiandosterone (DHEAS), which result in a decrease in glucose uptake due to decreased insulin receptor sensitivity and insulin action[8]
Poor quality of marriage is often associated with various indicators of poor health, including immunological and metabolic responses associated with the occurrence of type-2 diabetes
Summary
The prevalence of diabetes in the world is increasing. The International Diabetes Foundation (IDF) estimates that the number of people with DM in 2040 will increase around 54.7% compared to 2015. The facts showed that around two-thirds of the mental health problems of diabetic patients were not diagnosed and not treated. The increased of cortisol hormone due to stress will inhibit the work of the insulin hormone, so that blood sugar becomes increasingly high. Another negative consequences of stress conditions is the presence of sympathetic nerve stimulation which results in vascular vasoconstriction. It will increase the resistance of peripheral resistance. The purpose of this study was to analyze the biological factors that contribute to the distress of patient with DM type-2.
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