Abstract
Rodents exposed to the ambient atmosphere of Los Angeles throughout their lives have been studied in comparison with animals maintained in smog-filtered atmospheres. In aging inbred mice of certain strains, there was an increased incidence of pulmonary adenoma. In one strain mortality of males (but not females) during the first year of life was increased. Severe smog episodes caused lung tissue alterations at the ultrastructural level, especially in mice older than 15 months. Severe episodes produced transient increases in pulmonary resistance in old guinea pigs but no demonstrable chronic or cumulative effects on this parameter. In guinea pigs sensitized by prior stress treatment, urinary excretion of 17-ketogenic steroids was enhanced by ambient atmosphere exposure. After two or three years of exposure, rabbits exhibited reduced activity of glutamic oxalacetic transaminase in blood serum.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
