Abstract

The results of a study of the biological effect of feed probiotic additives “Subtilis-Zh” (0,04 ml/kg of feed) and “ATYSH” (0.08 g/kg of feed), which are based on cultures of bacteria B. subtilis, B. licheniformis, E. faecium and L. acidophilus, on growth, morphological and biochemical parameters of blood, as well as amino acid and chemical composition of carp muscle tissue. The analysis of the growth intensity showed a significant increase in body weight from the 4th week of the experiment in groups receiving separately the probiotic “Subtilis-Zh” and jointly the probiotics “Subtilis- Zh” and “ATYSH”. Hematological indicators demonstrate a significant increase in the concentration of leukocytes in the experimental group that consumed the complex of probiotic drugs “Subtilis-Zh” and “ATYSH” in comparison with the control by 19,8% (P < 0.05), respectively. A similar blood pattern was observed when studying a carp leukogram, where a significant increase in lymphocytes was found. The number of red blood cells in the blood corresponded to normal physiological values. At the same time, the indicator of hemoglobin content has increased significantly, which indicates active metabolic processes. The use of the feed probiotic additive “Subtilis-Zh” favorably affected the growth, development and hematological parameters of carp. The combined use of this drug with the feed probiotic additive “ATYSH” allowed to normalize the own bacterial flora of the intestine and strengthen the resistance of the fish organism to the effects of pathogens.

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