Abstract
Fir clubmoss Huperzia selago growing in Europe is a rich source of Huperzine A (selagine, HupA)(1.59mg g -1 d.w.) an effective, reversible and selective acetylcholinesterase (AChE) inhibitor, undergoing clinical trials as a potential medicine in Alzheimer disease and schizophrenia. Studies performed with modified Ellman's method have shown that apart from Hup A, other compounds with AChE and butyrylcholinesteraze (BuChE) inhibitory activity are present in the alkaloid extract of H. selago. Percentage inhibition range of the alkaloid extract fractions was
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