Abstract
We have evaluated antioxidant and antimicrobial activities of various solvents extracts from Pleurotus ostreatus . Organic solvents such as acetone, ethyl acetate, and ethanol were used to produce P. ostreatus extracts. Antioxidant activities were determined by measuring total polyphenol and flavonoid contents, DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) radical scavenging activity, and ABTS (2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activity. The acetone extract showed the highest antioxidant activities except total flavonoid contents. Antimicrobial activities of P. ostreatus extracts were determined against four strains of Gram-negative bacteria and eleven strains of Gram-positive bacteria including nine oral bacteria by disc diffusion method. The acetone extracts had antimicrobial activities against only B. subtilis and E. coli , whereas the other extracts inhibited the growth of most oral bacteria. These extracts showed a significant growth inhibition against S. sanguinis.
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