Abstract
Snowdrop is an iconic early spring flowering plant of the genus Galanthus (Amaryllidaceae). Galanthus species (Galanthus spp.) are economically important plants as ornaments. Galanthus spp has gained significance scientific and commercial interest due to the discovery of Galanthamine as symptomatic treatment drug for Alzhiermer disease. This review aims to discuss the bioactivities of Galanthus spp including anticholinesterase, antimicrobial, antioxidant and anticancer potential of the extracts and chemical constituents of Galanthus spp. This review highlights that Galanthus spp. as the exciting sources for drug discovery and nutraceutical development.
Highlights
Amaryllidaceae family comprises about 85 genera and classified into 1,100 perennial bulb species (Bulduk and Karafakıoglu, 2019)
It contains a variety of secondary metabolites such as flavonoids, phenolics, terpenoids and some important alkaloids that have shown to possess a broad spectrum of biological activities (Semerdjieva et al, 2019)
The results indicated that plants derived mannose-binding lections had strongest anti-coronavirus activitity and Galanthus nivalis was one of the coronavirus-inhibiting plants (Adams, 2020)
Summary
Amaryllidaceae family comprises about 85 genera and classified into 1,100 perennial bulb species (Bulduk and Karafakıoglu, 2019). The genus Galanthus, commonly known as “snowdrop” belongs to the family of Amaryllidaceae It is a small genus comprises about 20 species of bulbous perennial herbaceous plants, and a small number of subspecies, varieties and natural hybrids (Rønsted et al, 2013; World Checklist of Selected Plant Families, 2020). Snowdrop are economically important thanks to their ornamental potential and their use as landscape plants (Semerdjieva et al, 2019) Despite their ornamental properties, snowdrops have been used in folk medicine to treat pain, migraine and headache. Snowdrops have been used in folk medicine to treat pain, migraine and headache It contains a variety of secondary metabolites such as flavonoids, phenolics, terpenoids and some important alkaloids that have shown to possess a broad spectrum of biological activities (Semerdjieva et al, 2019). Over the past three decades, many alkaloids isolated from the Galanthus spp. including isoquinoline-like compounds such as caranine, narciclasine, tazettine, narwedine and montanine were reported to exhibit acetylcholinesterase inhibitory potential, antibacterial, antifungal, antiparasitic (malaria), antiviral, antioxidant, anticancer, anti-inflammatory
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