Abstract
The chromanol of hexahydrocoenzyme Q 4 was found to prevent encephalomalacia in the chick, the resorption-gestation syndrome in the rat, and to cure nutritional muscular dystrophy in the rabbit. The chromanol of vitamin K 1(20) also prevented encephalomalacia in the chick. Other compounds including hexahydrocoenzyme Q 4, chromenols of hexahydrocoenzyme Q 4 and coenzyme Q 10, and tocopheryl quinone were inactive in preventing encephalomalacia and the resorption-gestation syndrome. The chromanol of vitamin K 1(20) was effective in shortening prothrombin time in vitamin K-deficient rats, while the chromanol of hexahydrocoenzyme Q 4 and the chromenol of coenzyme Q 10 were ineffective.
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