Biological activities of Agrocybe praecox (spring fieldcap mushroom)

Abstract

Mushrooms, regarded as a significant component of the ecosystem, are utilised by individuals for various purposes. The present study aimed to investigate the biological activities of Agrocybe praecox (Pers.) Fayod, commonly referred to as the Spring Fieldcap mushroom. The ethanol extract of the mushroom was obtained with the Soxhlet apparatus. Subsequently, the quantification of total antioxidant, total oxidant, and oxidative stress index of the mushroom extract was conducted utilizing Rel Assay kits. The total phenolic content was determined using the Folin-Ciocalteu reagent. The agar dilution method was employed to assess the antimicrobial activity of the mushroom extract. The antiproliferative activity of the compound was assessed using A549 lung cancer cells. Elemental levels of the fungus were measured using the wet digestion method. The findings of the study revealed that the levels of the elements fell within the range reported in the existing literature. In addition, it was determined that the total antioxidant value was 2.97±0.08, the total oxidant value was 7.63±0.16, the oxidative stress index was 0.26±0.01, and the total phenolic content was 49.7±3.0 mg/g. It was found to be effective against microorganisms at concentrations between 50-200 µg/mL. Furthermore, it was ascertained that this mushroom exhibited antiproliferative activity, with the degree of activity being contingent upon the concentration of the extract. Consequently, it was determined that Agrocybe praecox exhibits potential as an antioxidant, antimicrobial, and anticancer agent.