Abstract
Pyracantha spp. are commonly called firethorn, and attract human attention due to their colorful berries. These berries are eaten globally as a traditional remedy for treating different stomach abnormalities, and as a cooking ingredient for folk diets. The present review aims to provide an overview on Pyracantha genus' geographical distribution and botanical description, traditional uses, phytochemical composition, biological activities and safety issues. Several biological activities have been reported to Pyracantha species, namely antioxidant, anti-inflammatory, antimicrobial, larvicidal and cytotoxic properties, most of them attributed to the use of their fruits. Pyracantha species phytochemical composition reveal the presence of interesting bioactive molecules, such as pyracrenic acid and fortuneanosides. The currently reported biological activities to these plants derive from in vitro and in vivo studies, so that clinical trials are needed to confirm these preclinical results. Nonetheless, Pyracantha species can be suggested as a safe herb useful to develop future drug formulations and functional foods.
Highlights
Cellular and Molecular BiologyBiological activities and health-promoting effects of Pyracantha genus: a key approach to the phytochemical’s potential
Pyracantha genus is an evergreen, thorny shrub belonging to the Rosaceae family, widely used in gardening and landscaping (1)
The present review aims to provide an overview on Pyracantha spp geographical distribution, botanical description, traditional uses, phytochemical
Summary
Biological activities and health-promoting effects of Pyracantha genus: a key approach to the phytochemical’s potential. Javad Sharifi-Rad1*#, Yasaman Taheri2#, Seyed Abdulmajid Ayatollahi[1,3], Nima Naderi[2], Nanjangud Venaktesh Anil Kumar[4], Niranjan Koirala[5], Sujan Khadka[5], Natallia Karazhan[6], Md Shahinozzaman[7], Surjit Sen[8,9], Krishnendu Acharya[8], Abhijit Dey[10], Miquel Martorell11,12*, Natália Martins13,14*
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