Abstract
Experiments were carried out on the effects of various linear-type furanocoumarins on the concentrations of lipids and glucose in rat plasma. It was found that bergapten and xanthotoxin cause hypolipidemia. In contrast, imperatorin, isoimperatorin, oxypeucedanin and oxypeucedanin hydrate cause hyperlipidemia. However, no effect on any lipid fraction in rat plasma was produced by isopimpinellin, phellopterin, ferulin, byakangelicin or sec-O-acetylbyakangelicin. Glucose level in rat plasma was increased by isopimpinellin and psoralen, and decreased by oxypeucedanin. These results suggest that the effects of linear-type furanocoumarins on lipid concentration in rat plasma depend upon whether substitution is present or not at the 5- and 8-positions of the skeleton and upon the kinds of substituents.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
