Abstract

The Orchidaceae family is appreciated worldwide due to the beauty of their flowers. In this context, Brazil is a continental country pleased with the occurrence of hundreds of species. However, little is known about the potential of orchids for therapeutically important studies. Therefore, this study aimed the isolation of bioactive molecules from South Brazilian orchid Miltonia flavescens Lindl.. Bioguided studies with the fungus Cladosporium herbarum allowed the identification of hidrocinnamic acid as the antifungal active substance. In addition, chloroform partition (CP) showed an interesting activity against cancer cell lines. CP fractionation afforded the isolation of the flavonoid hortensin, wich was active against seven human cancer cell lines, been selective for MCF-7 breast carcinoma with GI50=6.8µg/mL. Acknowledgement: Fundação Araucária (Brazil).

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call