Biogenic synthesis of silver nanoparticles using Priva cordifolia leaf extract (PC@AgNPs) a potent antioxidant, antibacterial and catalytic activity

Abstract

A nanoparticle preparation (PC@AgNPs), synthesized biogenically using Priva cordifolia leaf extract was found to possess quenching property of stable DPPH and ABTS in dose dependent manner. The PC@AgNPs showed well-established physicochemical stability with respect to temperature, PH and salinity. It showed a broad bactericidal effect against 10 pathogenic bacteria, notably Staphylococcus aureus, Escherichia coli, Shigella flexneri and Vibrio parahaemolyticus. Its non-toxicity up to 500 µg mL−1 concentration to peripheral blood mononuclear cells was recorded. However, its toxic effect against human lung carcinoma cells and human breast adenocarcinoma cell lines at a dose of 500 and 300 µg mL−1 respectively was clearly evident. The catalytic efficiency of PC@AgNPs was demonstrated in methylene blue and methyl orange dye degradation. The studies have suggested possible applications of PC@AgNPs in future biomedical, pharmaceutical, and environmental applications.