Biogenic and eco-benign synthesis of silver nanoparticles using jujube core extract and its performance in catalytic and pharmaceutical applications: Removal of industrial contaminants and in-vitro antibacterial and anticancer activities

Abstract

Biosynthesis of nanoparticles has been rapidly developed in various fields, due to their broad spectrum of applications in the fields of environmental, pharmacology, and medicine. In this study, facile, rapid, eco-friendly and cost-effective method was used to green synthesis of silver nanoparticles (AgNPs) using jujube core extract (AgNPs- JCE ) and then used as antibacterial, anticancer and catalytic agents. The reaction parameters such as AgNO 3 concentration (1, 5, 10, 20 and 40 mM), reaction time (5, 30 and 60 min) and pH (without pH, 10 and 12) were discussed and optimized. The surface plasmon resonance peak at about 420 nm in the UV–Vis absorption spectrum confirmed the green synthesis of silver nanoparticles. Microscopic results revealed that the synthesized AgNPs- JCE were spherical in morphology with a size range of 25–35 nm.In addition, the subject AgNPs promising catalytic properties in the degradation of pollutants including rhodamine b (RhB) and eriochrome black T (EBT) as cationic and anionic contaminant under UV and visible light irradiations. The photocatalyst (AgNPs- JCE ) exhibited the degradation of 90.9 % and 84.7% for RhB and EBT contaminants after 80 min under UV irradiation, respectively. The antibacterial activities of AgNPs- JCE was checked against E. coli as Gram-positive bacteria and K. pneumoniae and S. aureus as Gram-negative bacteria with MIC and MBC values of (1.26 and 1.26 μ g/ml), (2.5 and 2.5 μ g/ml), and (2.5 and 10 μ g/ml), respectively. Finally, the cytotoxicity of synthesized nanoparticles against AGS as human stomach cancer cell line was determined at several concentrations (2.5, 5, 10, 20, 50, and 100 μ g/ml) using MTT assay. Finding of this research suggested the suitability of AgNPs- JCE as pollutants degradation, antibacterial and anticancer drug development. • First report of biogenic silver nanoparticles synthesis using jujube core extract. • Green synthesized of AgNPs was analyzed by UV/Vis, FT-IR, XRD, EDS, FESEM and TEM. • Exhibited potential photocatalytic degradation in rhodamine b (RhB) and eriochrome black T (EBT) under both UV and sunlight irradiations. • Biosynthesized AgNPs showed good antibacterial activity against gram-positive and gram-negative bacteria. • AgNPs exhibited excellent anticancer activity against AGS as human stomach cancer cell line.