Abstract

Radioactive serpentine which was obtained from Rauwolfia serpentina plants which had been fed tryptophan-2-C 14 was degraded systematically and was found to be labeled solely at C-5. This result indicates that tryptophan is a direct precursor of the β-carboline moiety of this alkaloid. Radioactive reserpine which was obtained from the same feeding experiment was labeled only on the reserpic acid part of the alkaloid.

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