Abstract
AbstractThis paper aimed to gather information regarding mechanism of biofilm formation and development of resistance of the fungi mainly the candida species to antifungal therapy from literature through 1996-2012. We have carried out a detailed search in the National Library of Medicine's PubMed database, Google search and Science Direct to include all studies and reviews published in English language. The key words used for the search were biofilm, Candida, antimicrobial resistance, denture stomatitis and Candidiasis. This paper tries to explain the mechanism of biofilm formation, factors which initiate and propagate biofilm production and certain special features like thigmotropism and quorum sensing which are responsible for development of resistance in these yeasts.
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