Biofilm Production of Candida Isolated from Blood and Urine

Abstract

Biofilm production has been noted as a potential virulence factors in Candida species responsible for catheter related invasive Candida infection in most of the patients especially patientsadmitted in ICU early detection of Biofilm production is helpful in treating of patients and clinical decision keeping this in mind we conducted the study detection of Biofilm production in Candida species isolated from blood and urine patients with indwelling catheters total 80 Candida species were isolated 40 in blood and 40 in urine isolates include C. krusei, C.albicans, C. tropicalis, C. parapsilosis,C. glabrata and C.guilliermondii. The organisms grown in sabourauds liquid medium containing 8% of glucose. Biofilm production was determined the Biofilm production was less frequent in Candida albicans as compared to non-albicans species. The data conclude that Biofilm production in vitro may has relation to pathogenesis of Candida isolates species causing candidemia in ICU patients with indwelling catheters.