Abstract

Biofilm formation is a method for bacteria to adapt for its survival, to put it another way, it act as a shield and prevents bacterial eradication. Microbial biofilms are one of the major reasons for progession of periradicular pathology. The article aims to concise and stratify the literature about, various factors that leads to biofilm formation their adaptation mechanisms, biofilms role in progression of peri-radicular infections, models developed to create biofilms, observation techniques of endodontic biofilms, and the effects of root canal irrigants and medicaments as well as lasers on endodontic biofilms.

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