Abstract
BioEssaysVolume 37, Issue 7 Cover PictureFree Access BioEssays 7∕2015 First published: 22 June 2015 https://doi.org/10.1002/bies.201570071AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Pack it tightly. On pages 755–766 Marc Kschonsak and Christian Haering review how chromosomes are condensed before cell division, and which proteins and molecular machines are involved in this process. The authors discuss a three-step model for the formation of these mitotic chromosomes. The fi rst step, linear chromatin looping, takes place early during prophase and involves condensin II complexes. This is followed by axial compression during late prophase. This second step is accompanied by the action of topoisomerase IIα and the release of cohesion from chromosomes. The third step is lateral compression and requires the action of condensin I complexes. (Background image from fotolia - nobeastsofi erce.) Volume37, Issue7July 2015 RelatedInformation
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