Abstract
BioEssaysVolume 40, Issue 3 1870031 Cover PictureFree Access BioEssays 3∕2018 First published: 21 February 2018 https://doi.org/10.1002/bies.201870031AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Initial production of hydrogen peroxide (H2O2) and other reactive oxygen species was not a result of increased O2 levels in the atmosphere but rather was a crucial consequence of early Earth's weakly oxic microenvironments. However, as discussed in article 1700158 by Taverne et al., Earth's oxygen cycle did coincide with the evolution of major redox pathways (NOX, Nrf-2 and HIF pathways) that were preserved throughout time and played a major role in Metazoan diversification and longevity. [Cover design: isontwerp.nl, Eindhoven, The Netherlands] Volume40, Issue3March 20181870031 RelatedInformation
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