Bioengineering corneal transplantation for treatment of herpes simplex keratitis complicated corneal leukoplakia

Abstract

<p indent="0mm">Bioengineering cornea used for lamellar keratoplasty holds significant efficacy, high safety and good prognosis in the treatment of severe corneal disorders, which may be used as a substitute when donor cornea is deficient. The most important characteristics to be considered for bioengineering cornea are suitable mechanical properties, biocompatibility, and transparency, which have been shown to mimic the human corneal extracellular matrix and enhance cell differentiation. Currently, the bioengineering corneal transplantation is the most common tissue equivalent in the treatment of infectious corneal ulcer. We reports here a case of bioengineering corneal transplantation for herpes simplex keratitis (HSK) complicated corneal leukoplakia.