Abstract
The present study was aimed to examine the antibacterial potential of Caulerpa corynephora Montagne, Caulerpa scalpelliformis (R. Br.) Weber-van Bosse, Chaetomorpha antennia (Bory de Saint-Vincent) Kutzing, Enteromorpha compressa (L.) Grev., Halimeda macroloba Decsne., Ulva fasciata Delile and Ulva lactuca Linn. from southern east coast of Tamil Nadu, India. For the bioefficacy analysis the pathogens viz., Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Serratia marcescens, Salmonella typhi, Acinetobacter calcoaceticus, Enterobacter cloacae, Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes and Bacillus cereus were procured from Scadder Laboratories. The antibacterial activity was determined by the paper disc diffusion method. 30µg of crude extracts of selected seaweeds were used for the analysis. 30µg and 30µl of the respective solvents were used as positive and negative control. Among the five different extracts examined, antibacterial activities are observed in hexane, petroleum ether, chloroform and ethanolic extracts with varied frequency. Aqueous extracts were failed to show activity against the tested twelve pathogens. In the present study, variability in the antibacterial activity may be related to variability in the bioactive principles present in different seaweeds and organic solvents used for extraction of bioactive compounds. Further purification of the extracts may yield a novel antibacterial drug to treat various diseases typhoid, diarrhoea, pneumonia, meningitis, osteomyelitis, endocarditis, nausea, skin infections etc.
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