Abstract
Zinc (Zn) alloys are expected to be a potential biodegradable bone implant material due to its biodegradability, good biological effect, and easy formability. However, the lower mechanical properties and low degradation rate of most cast Zn alloys still make it difficult to match the mechanical properties and healing cycle requirements of degradable bone implants. In this work, the degradable Zn1Mg-xCe (x=0.1, 0.2, and 0.3 wt%) alloys with high comprehensive mechanical properties, suitable degradation rate (CRimm) and cytocompatibility were prepared by cerium (Ce) alloying followed by hot-rolling for load-bearing bone-implant material. With the increase of Ce content, the Zn-1Mg-xCe alloys showed a gradual increase in mechanical strength, hardness, and CRimm and decreased elongation at break and cell viability. Zn-1Mg-0.2Ce exhibited the best comprehensive performance match among all Zn-1Mg-xCe, including a moderate ultimate tensile strength of ∼263 MPa, yield strength of ∼171 MPa, elongation at break of ∼14.4 %, strength-elongation product of ∼3.8 GPa%, hardness of ∼90.6 HV, CRimm of ∼62 μm/y, and cytocompatibility towards 3T3 cells.
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