Abstract

Key steps in the biodegradable stent revolution, including the first-in-man results of magnesium1,2 and poly-L-lactide (PLLA) stents,3,4 have been reported in The Lancet. With more than 60 000 Absorb bioresorbable vascular scaffolds implanted in the past 3 years, a randomised comparison of metallic and fully bioabsorbable stents, both eluting the antiproliferative drug everolimus, is now presented by Patrick Serruys and colleagues.5 The ABSORB II trial had a 2:1 single-masked design and a small sample population of 501 patients, with sophisticated coprimary endpoints of nitrate-induced vasomotion and changes in minimum lumen diameter (in-stent late loss) at 3 years.

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