BIODEGRADABLE SILICA FIBERS FROM SOLS

Abstract

Biodegradable silica fibers for reinforcement of medical implants were successfully prepared by sol-gel processing. The spinnable precursor is based on TEOS and shows a characteristic, non-Newtonian rheological behavior in the presence of sol-particles of size 4 to 5 nm. This property suggests a non-covalent, supramolecular structure of the spinnable silica sol. The fibers obtained were characterized using IR, NMR and thermal analysis as well as biological and mechanical testing. The degradation rate of fibers was tested in continuous flow experiments. The results demonstrate a good potential of the fibers for medical applications.