Abstract
In article number 2000806 by Richard M. Day and co-workers, highly porous biodegradable films are prepared using thermally-induced phase separation. In vivo implantation of the films into ischemic tissue stimulates increased expression of pro-angiogenic growth factor genes. This provides a favourable local environment for neovascularization, increased tissue perfusion, and therapeutic angiogenesis in ischemic tissue. The findings pave the way to establishing new materials-based strategies to achieve therapeutic angiogenesis.
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