BioDADPep: A Bioinformatics database for anti diabetic peptides.

Susanta Roy

doi:10.6026/97320630015780

Abstract

The increasing number of cases for diabetes worldwide is a concern. Therefore, it is of interest to design therapeutic peptides to overcome side effects caused by the available drugs. It should be noted that data on several known anti-diabetic peptides is available in the literature in an organized manner. Hence, it is of interest to collect, glean and store such data in form of a searchable database supported by RDBMS. Data on anti-diabetic peptides and their related data are collected from the literature using manual search. Data on related peptides from other databases (THPdb, ADP3, LAMP, AHTPDB, AVPdb, BioPepDB, CancerPPD, CPPsite, DRAMP, SATPdb, CAMPR3 and MBPDB) are also included after adequate curation. Thus, we describe the development and utility of BioDADPep, a Bioinformatics database for anti-diabetic peptides. The database has cross-reference for antidiabetic peptides. The database is enabled with a web-based GUI using a simple Google-like search function. Data presented in BioDADPep finds application in the design of an effective anti-diabetic peptide.

Highlights

Diabetes mellitus is a pandemic non-communicable chronic autoimmune disease affecting the quality of life
It should be noted that data on several known anti-diabetic peptides is available in the literature in an organized manner
Data presented in BioDADPep finds application in the design of an effective anti-diabetic peptide

Summary

Introduction

Diabetes mellitus is a pandemic non-communicable chronic autoimmune disease affecting the quality of life (diet and lifestyle). It should be noted that data on several known anti-diabetic peptides is available in the literature in an organized manner. Data on anti-diabetic peptides and their related data are collected from the literature using manual search. Data on related peptides from other databases (THPdb, ADP3, LAMP, AHTPDB, AVPdb, BioPepDB, CancerPPD, CPPsite, DRAMP, SATPdb, CAMPR3 and MBPDB) are included after adequate curation.

Results

Conclusion