Abstract

Genome sequencing capabilities and capacity are so advanced that the genomes of virtually all microbial species of interest are likely to be deciphered during the next decade. Improved means for interpreting and applying this sequence information enhance its value. The BioCyc database collection and website include data for more than 1,000 microbial genomes as well as tools for analyzing that information. These resources help users to address key questions such as: What are the functions of the upstream and downstream neighbors of a gene? How far apart are the genes, and are they likely to form an operon? What is the sequence of the gene and DNA segments near it? What metabolic pathway does a gene play a role in?

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