Abstract
Nowadays, most products for dental restoration are produced from acrylic resins based on heat-cured Poly(Methyl MethAcrylate) (PMMA). The addition of metal nanoparticles to organic materials is known to increase the surface hydrophobicity and to reduce adherence to biomolecules. This paper describes the use of nanostructured materials, TiO2and Fe2O3, for simultaneously coloring and/or improving the antimicrobial properties of PMMA resins. Nanoparticles of metal oxides were included during suspension polymerization to produce hybrid metal oxides-alginate-containing PMMA. Metal oxide nanoparticles were characterized by dynamic light scattering, and X-ray diffraction. Physicochemical characterization of synthesized resins was assessed by a combination of spectroscopy, scanning electron microscopy, viscometry, porosity, and mechanical tests. Adherence ofCandida albicanscells and cellular compatibility assays were performed to explore biocompatibility and microbial adhesion of standard and novel materials. Our results show that introduction of biocompatible metal nanoparticles is a suitable means for the improvement of conventional acrylic dental resins.
Highlights
To date, up to 95% dental prostheses are composed of Poly(Methyl MethAcrylate) (PMMA), due to its advantages, including its optical properties, biocompatibility, and aesthetics [1, 2]
The pigments were characterized by X-ray diffraction (XRD) in order to search whether specific crystal phases with antimicrobial properties are present in the powders
In this study, nanosized TiO2 and Fe2O3 particles were employed during synthesis of PMMA
Summary
Up to 95% dental prostheses are composed of Poly(Methyl MethAcrylate) (PMMA), due to its advantages, including its optical properties, biocompatibility, and aesthetics [1, 2]. Adhesion and plaque formation onto PMMA-based resins is a common source of oral cavity infections and stomatitis [3]. These affections may cmtinvolve a variety of human pathogens and have been commonly associated to the oral commensal Candida albicans [4], an opportunistic pathogen causing emergent disease within immune suppressed patients [5]. The search for innovative solutions addressing these problems is of special interest in the development of acrylic materials-based implants
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
