Abstract
High-density polyethylene–hydroxyapatite (HDPE–HA) composites with different filler content (5–20 %) were synthesized by in situ ethylene polymerization. Good filler dispersion was observed without formation of agglomerates. Osteoblast cell behavior in HDPE–HA composites was evaluated in terms of adhesion, alkaline phosphatase activity and proliferation. Fluorescence and scanning electron microscopy results showed good cell adhesion and proliferation, and extensive filopodium-like protrusion connected to hydroxyapatite particles.
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