Biocompatibility screening of Mo–Si–Ta glassy alloy films sputtered on additive manufactured Ti–6Al–4V implant prototypes and PCL scaffolds

Abstract

A ternary system of amorphous alloy with the components Mo, Ti, and Si with the composition Mo54Si33Ta13 has been chosen as the surface coating for the implantable materials to improve Ti6Al4V bioactivity. Ti6Al4V alloy metal powders were used to create the implant prototypes with the 3D metal printer. With the aid of a DC magnetron, the films are sputtered onto the implant prototypes. Elemental composition, amorphous nature, surface chemistry and topography of the as-fabricated microstructure films were comprehensively analysed using X-ray diffraction analysis, X-ray photoelectron spectroscopy and electron/atomic force microscopic techniques. The mechanical properties were studied from Nano indentation method. The coatings were confirmed to be cytocompatible determined from the in-vitro biocompatibility investigations using human osteosarcoma cells. The electrochemical corrosion studies carried out in SBF showed the higher corrosion resistance for the thin film metallic glass (TFMG)-coated customized 3D printed Ti-alloy implants than the pristine specimen.