Abstract
Currently many materials have been used with pulpotomies in primary teeth. These include MTA, that as a direct pulp capping material seemed to stimulate natural dentin repair at pulpal exposure sites. The composition of this product is based on Portland cement. Later, white MTA was introduced as an esthetic improvement over the original material (grey MTA). A number of studies have been performed on this new material to determine if it shows the same properties as gray MTA. The biocompatibility of MTA has been previously investigated in vitro using a number of the cell lines. However, the use of primary cultures (in this case pulp fibroblasts) is often desirable. Objective: The objective of this in vitro study was to compare the cytotoxicity in a pulp fibroblasts culture, of regular (grey) MTA, white MTA and Portland cement Material and method: A cytotoxicity study was made in a primary pulp fibroblasts culture of MTA, white and grey, and a grey Portland cement. Results: Without taking into account concentrations, there were no significant differences between regular MTA and white MTA (p=0.146). A significant difference was recorded between grey Portland cement, which were less biocompatible, and regular MTA (p=0.029), and white MTA (p=0.002). Conclusion: The results found in the present study might be an additional argument to support that MTA is biocompatible, and may be considered as a pulp dressing agent in pulpotomized primary molars with carious pulp exposures. However, the grey Portland cement, under the same conditions, shows reduced biocompatibility.
Highlights
The pulpotomy is one of the most frequent treatment in the primary dentition
White mineral trioxide aggregate (MTA) was introduced as an esthetic improvement over the original material
The use of primary cultures is often desirable, since they may offer increased specific sensitivity to the test agent or substance [32,33]. The objective of this in vitro study was to compare the cytotoxicity in a pulp fibroblasts culture, of regular MTA, white MTA and Portland cement
Summary
The pulpotomy is one of the most frequent treatment in the primary dentition. It consists of the amputation of the coronal pulp affected or infected while the radicular pulp tissue is preserved. The radicular pulp stumps should be covered with a pulpal dressing, and later the tooth is restored. The material to be used for pulpotomies should be bactericidal and harmless to the pulpal tissue and surrounding structures and not interfere with the physiological process of root resorption [1]. These include electrosurgery, laser, ferric sulfate, bone morphogenetic protein and osteogeneic protein [2,3,4,5]. The physical and chemical properties of a root-end filling material, mineral trioxide aggregate (MTA) were described by Torabinejad et al [6]
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