Abstract
To study the suitability of resorbable polylactides for reconstruction in middle ear surgery. Twenty-four chinchillas. Twenty chinchillas were operated on using 2 types of polylactides inserted into the middle ear and outer ear canal, 10 animals in each group. At 6 months, the animals were killed, and their temporal bones were removed for sectioning. Degree of inflammation, fibrosis, degradation of polylactide material, and new bone formation were assessed histologically. Polylactide implants caused only a mild local inflammation, with no difference between the 2 materials tested. Polylactide acid-based middle ear implants were successfully used in the reconstructive middle ear surgery. Resorption occurred without complications.
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