Abstract
The coronavirus is something of a wolf in sheep’s clothing. Originally identified as a large pleomorphic enveloped RNA virus with unique external morphological features and a helical internal nucleocapsid (Tyrrell et al., 1975), the close parallels with negative strand RNA viruses prompted many investigators to search for a coronavirion transcriptase. It soon became clear however, that, despite their morphological appearance, the coronaviruses possess an infectious genome RNA which must, by definition, be of positive polarity.
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