Abstract
The ABO blood group polymorphism of humans are known to be determined by the expression of A, B or H (O) antigens which are terminal neutral glycan sequences found in abundance on glycoprotein's and glycolipids. Apart from their matching role in blood transfusion these specific antigens are known to play their important role in regulation of various biochemical and immunological reactions in the body and are with platelets as intrinsic determinants and extrinsically absorbed antigens and exist both on glycosphingolipids and glycoprotein's. Throughout the years there have been many reviews of the ABO blood group system, covering different aspects of this fascinating topic. This article provides a brief introduction to this amazing complex blood group system and our intension is to focus on the biochemistry of ABO blood groups.
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