Abstract

Biochemistry during the Life and Times of Hans Krebs and Fritz Lipmann

Highlights

  • This essay reviews some of the types of problems under investigation during the period of 1940 –1950 and the influence two exceptional scientists would have on my early development as a biochemist

  • A new finding did emerge, namely, in its conversion to liver glycogen the carboxyl carbon of lactic acid is replaced in part with carbon originating from carbon dioxide (4, 5)

  • Krebs initially proposed the involvement of a seven-carbon compound, oxalcitraconic acid, which by oxidative decarboxylation would yield the six-carbon citric acid

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Summary

Introduction

This essay reviews some of the types of problems under investigation during the period of 1940 –1950 and the influence two exceptional scientists would have on my early development as a biochemist. Biochemistry during the Life and Times of Hans Krebs and Fritz Lipmann Earl Evans (9) of the University of Chicago had spent a sabbatical year in Krebs’ laboratory in England working on reactions of a cycle of reactions that had been proposed by Krebs

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