Biochemistry and Function of Phagocytes

Abstract

Morphology.- Three Types of Granule Formed in Guinea Pig and Rat Heterophil Granulocytes.- Locomotion of Phagocytes.- Leucocyte Activation and the Assessment of Leucocyte Locomotion and Chemotaxis.- Distribution of Actin-Binding Protein and Myosin in Neutrophils During Chemotaxis and Phagocytosis.- Interaction Between Neutrophils and Mediators of Inflammation.- A Short Transient Increase in Cyclic Adenosine 3?, 5?-Monophosphate Levels of Neutrophil Granulocytes Following Exposure to Chemotactic Factors.- Neutrophil Migration and Orientation Under Agarose: Findings in Patients With the Immotile Cilia Syndrome and Effects of Cytochalasin B and Vinblastine.- Cytotoxic Activity of Phagocytes.- A Differential Responsiveness of In Vitro Differentiating Mononuclear Phagocytes From Bone Marrows of Normal and Inflamed Mice to Lymphokines and Poly I * Poly C.- The Oxygen-Dependent Antibody-Dependent Cell-Mediated Cytotoxicity of Human Monocytes and Neutrophils.- Macrophage Activation for Tumor Cytotoxicity: Reactivity of Peritoneal and Bone Marrow Macrophages.- Cytotoxicity on Tumor Cells of Human Macrophages: Functional Status of Tumor-Associated Effector Cells.- Studies on the Recognition of Xenogeneic Cells by Nonimmune Macrophages. II. Separate Signals Triggered by Cytostasis and Cytolysis.- Genetic Aspects of Macrophage Activation for Tumor Cytotoxicity.- Microbicidal Activity of Phagocytes.- O2-Independent Killing of Gram-Negative Bacteria by Intact Granulocytes. The Role of a Potent Bactericidal Membrane-Perturbing Protein.- The Extracellular Stimulation of Intracellular Killing by Phagocytes.- Molecular Mechanism of the Bactericidal Action of Myeloperoxidase-H2O2 -Chloride.- The Role of the Cell Membrane in the Killing Mechanism of Polymorphonuclear Leucoctyes (PMN).- Leptospires Macrophage Interactions.- Relationship Between the Enchanced Oxidative Metabolism and the Enhanced Microbicidal Activity of Activated Macrophages.- Release of Superoxide Anion and Enhanced Candidacidal Activity as a Manifestation of Macrophage Activation: Studies with Muramyl Dipeptide.- Killing of Leishmania donovani Amastigotes by Murine Macrophages.- Selective Depression of Phagocytes Intracellular Killing Activity.- Secretory Activity of Phagocytes.- Modulation of the Inflammatory Response by the Neutrophil Myeloperoxidase System.- Elastase Secretion by Mouse Peritoneal Macrophages: Effects of Rifampin and Corticosteroids.- Synthesis and Release of Factor Increasing Monocytopoiesis (FIM) by Macrophages.- Biochemical and Biological Characteristics of Leucocyte Proteinase Inhibitors.- Oxidative Damage to Lysosomal Enzymes in Human Phagocytosing Neutrophils.- The Release of Platelet-Activating Factor During Phagocytosis by Polymorphonuclear Neutrophils and Monocytes.- The Secretion of Lysosomal Enzymes by Human Polymorphonuclear Leucocytes (PMN) and Its Modulation by Serum Complement.- The Bovine Neutrophil: Separation and Partial Characterization of Plasma Membrane and Cytoplasmic Granules.- Biochemistry of Phagocytes.- The Respiratory Burst of Phagocytic Cells: Facts and Problems.- Discrepancies in the Oxygen Balance of Whole Human Neutrophils and Neutrophil Homogenates.- Neutrophil Activation Studied Using Two Indirect Probes of Membrane Potential Which Respond by Different Fluorescence Mechanisms.- Apparent Km of Leukocyte O2? and H2O2 Forming Enzyme for Oxygen.- Formation of Superoxide Anions and Hydrogen Peroxide by Polymorphonuclear Leukocytes Stimulated With Cytochalasin.- Hydrogen Peroxide Production in a Cell-Free System: Evidence for the Involvement of a Chain Reaction.- The Respiratory Burst in Human Polymorphonuclear Leucocytes Stimulated by Particles.- Stimulation of the Hexose Monophosphate Shunt Activity in Human Polymorphonuclear Leukocytes.- The Nature and Function of the Microbicidal Oxidase System of Neutrophils.- Chemiluminescence and the Study of Phagocyte Redox Metabolism.- An Alternative Mechanism for the Production of Hydroxyl Radicals by Stimulated Neutrophils.- Superoxide Dismutases and the Oxidative Burst in Human Blood Polymorphonuclear Leukocytes.- Role of Serine Proteases in Superoxide Production by Human Neutrophils, Monocytes and Basophils.- Release of the Membrane-Calcium and its Relation to the Superoxide Formation by Polymorphonuclear Leukocytes.- ATP-Driven Ca2+ Pump Activity of Macrophage and Neutrophil Plasma Membrane.- Ca2+ Transport and Surface Membrane ATPase in Macrophages.- Effect of Ionophores on Lymphocyte Cellular Metabolism.- Peroxidatic Activity Distinct from Myeloperoxidase in Human Monocytes Cultured in Vitro and in Alveolar Macrophages.- Characterization of the Peroxidase in Human Eosinophils.- Stimulation or Activation of Eosinophils in Vivo During Eosinophilia: Possible Role of Arachidonic Acid Metabolism.- Factors Affecting Phagocyte Functions.- Platelet Leukocyte Interactions II In-Vivo Correction of Chediak-Higashi Leukocyte Function with Serotonin or Normal Platelets.- Physicochemical Surface Changes on Phagocytic Cells During Differentiation in Relation to Chemotaxis and Phagocytosis.- Mechanism of Hexose Transport in Human Polymorphonuclear Leukocytes.- Tuftsin and Substance P as Modulators of Phagocyte Functions.- The Effect of Hyaluronic Acid on Neutrophil Function in Vitro and in Vivo.- Expression of Fc and C3b Receptors and Intracellular Distribution of Bacteria in Rat Macrophages.- Monocyte Activation by Immune Complexes of Patients with SLE.- Clinical Aspects of Phagocyte Functions.- Nucleotide Concentrations in Leucocytes and Their Use in Controlling the Quality of Cell Preparations.- Resting and Stimulated Chemiluminescence of Polymorphonuclear Leukocytes: A Clinical Approach.- Deficient Phagocytosis Secondary to Breakdown of Opsonic Factors in Infected Exudates.- Congenital and Acquired Lactoferrin Deficiencies in Neutrophils.- Functional and Metabolic Abnormalities of Diabetic Monocytes.- Enzymatic Deficiency in Monocytes from Patients with Chronic Granulomatous Disease.- Use and Results of Neutrophil Function Testing in Pediatric Immunology.- The Effect of Influenza Virus on Oxygen-Dependent Metabolism of Human Neutrophils.- Chronic Granulomatous Disease, Kx Negative Neutrophils and Linkage with Xg.- Round Table on the Clinical Application of Leucocyte Function Tests.- Contributors.