Abstract
Women diagnosed with gestational diabetes mellitus have an increased risk of developing diabetes mellitus, which is a known risk factor for cardiovascular disease and insulin resistance. In the recently published article by Zajdenverg et al., they aimed to identify endothelial dysfunction and cardiovascular risk factors in women with previous gestational diabetes mellitus. However, authors did not evaluate the role of total homocysteine, which has important effects for endothelial dysfunction. Vitamin B12 and folic acid are important vitamins since their deficiency may lead to the probable microvascular abnormalities by increasing the tHcy, which is an independent risk factor for endothelial dysfunction.
Highlights
Women diagnosed with gestational diabetes mellitus have an increased risk of developing diabetes mellitus, which is a known risk factor for cardiovascular disease and insulin resistance
Endothelial dysfunction and cardiovascular risk factors were aimed to identify in women with previous gestational diabetes mellitus
Authors did not evaluate the role of total homocysteine, which has important effects for the endothelial dysfunction
Summary
Women diagnosed with gestational diabetes mellitus have an increased risk of developing diabetes mellitus, which is a known risk factor for cardiovascular disease and insulin resistance. Dear Editor We read with great interest the recently published article by Zajdenverg et al [1]. Endothelial dysfunction and cardiovascular risk factors were aimed to identify in women with previous gestational diabetes mellitus (pGDM). Significant differences were found in some cardiovascular risk factors when compared to others, as well as microvascular abnormalities (papillae rectification) in young women with pGDM, even with normal OGTT.
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