Biochemical Parameters Determination for Prognosis of Retinal Diseases and their Relationship to Cataract, Diabetes and Hypertension Patients in Ibn Al-Haytham Hospital in Baghdad-Iraq

Abstract

The role of serum retinol activity in association with the Blood sugar level, and their link as biochemical marker risk for lens inflammation and damage stage under pandemic, for the Retinal disease patients with cataract, hypertension, and diabetes, and in healthy for both genders. Total of seventy-five patients and thirty healthy control have been studied. Retinal disease patients were subdivided on the basis of pathological condition into three subgroups (First group was cataract, second was hypertension, and the third group was diabetes. Assessment, of serum retinol activity, and blood glucose levels were done for all groups. The concentricity of serum retinol levels is decreased in diabetic patients than control (13.147±7.195 (μmol/L) with 21.930±16.241 (μmol/L) versus P = 0.011)), while for cataract patients, they showed extremely similar concentricity of serum retinol levels to healthy (20.760±15.941 (μmol/L) with P = 0.790), whilst the retinol-activity was exhibited to be higher in hypertension patients (24.190±21.972 (μmol/L) versus P = 0.663). retinol activity is correlated significantly negatively with both diabetic patients and cataract. Moreover, blood sugar levels are increased in diabetes than control (10.256±4.119 (μmol/L) versus 5.365±1.084 (μmol/L) with P = 0.0001), in comparison with cataract (5.288±0.9560 (μmol/L) with P = 782). The retinol levels are correlated significantly negatively for diabetic and cataract patients. The purpose of this work: is to investigate association between retinal diseases with cataract hypertension & diabetes for risk of fasting at least eight hours in Ramadan and out of Ramadan time, and directly pre surgery gets started by artificial intraocular lens, and by estimation of retinol and blood sugar concentrations.