Abstract

This is an integrative literature review with the objective of identifying the relationship between biochemical parameters and the nutritional status of surgical patients with cancer of the gastrointestinal tract, developed in April 2019, encompassing the databases SCOPUS (Elsevier), PubMed Central® (PMC), and the Cochrane Virtual Health Library (BVS). We used the terms "Gastrointestinal Neoplasm" AND "Nutritional Status" AND "Blood Chemical Analysis" with the aid of the Academical software after the protocol validation. Out of 147 articles analyzed, seven were included in the review, as they met the inclusion criteria. There were relevant associations between biochemical parameters and nutritional status. Impaired nutritional status can negatively influence the postoperative outcome. The monitoring of interdisciplinary teams can assist in the recovery of these patients and prevent unfavorable outcomes.

Highlights

  • Cancer is a set of diseases characterized by the accumulation of progressive and disordered mutations in the genome of a cell[1]. These modifications can occur in special genes, called proto-oncogenes, which are inactive in normal cells

  • This study aimed to identify the relationship of biochemical parameters with the nutritional status of surgical patients with gastrointestinal tract cancer

  • We should note that the Cochrane Library includes the bases Medical Literature Analysis and Retrieval System online (MEDLINE), Scientific Eletronic Library Online (SciELO), and the Latin American and Caribbean Literature in Health Sciences (LILACS)

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Summary

Introduction

Cancer is a set of diseases characterized by the accumulation of progressive and disordered mutations in the genome of a cell[1] These modifications can occur in special genes, called proto-oncogenes, which are inactive in normal cells. The interaction between the host’s metabolic state, nutritional aspects, physical activity and other environmental exposures throughout life are parameters involved in the protection or susceptibility to the onset of cancer[3]. It is estimated for Brazil, in each year of the 2020-2022 triennium, the occurrence of 625,000 new cases of cancer. Among the most common cancers are non-melanoma skin cancers, followed by breast and prostate, colon and rectum, lung, and stomach tumors[4]

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