Biochemical mechanisms in heart function

Abstract

I: Calcium movements and cellular metabolism.- Control of cardiac performance by Ca-turnover.- Deformation of the Bowditch staircase in Ca2+-overloaded mammalian cardiac tissue - A calcium phenomenon?.- Cooperative interaction between Ca2+ binding sites in the hydrophylic loop of the Na+-Ca2+ exchanger.- E-1020, a water soluble imidazopyridine, has direct effects on Ca2+-dependent force and ATP hydrolysis of canine and bovine cardiac myofilaments.- Primary cultures of cardiac muscle cells as models for investigation of protein glycosylation.- Influence of glycosylation inhibitors on dihydropyridine binding to cardiac cells.- Comparative study of cardiac electrophysiological effects of atrial natriuretic peptide.- Effect of TaiCatoxin (TCX) on the electrophysiological, mechanical and biochemical characteristics of spontaneously beating ventricular cardiomyocytes.- Pharmacological characteristics of endothelin receptors in the rabbit ventricular myocardium: The nonselective endothelin receptor antagonist PD 145065 antagonizes the positive inotropic effect of endothelin-3 but not of endothelin-1.- Involvement of nitric oxide synthase and protein kinase C activation on chagasic antibodies action upon cardiac contractility.- Kinetics of myocardial phospholipase D.- Is cysteine residue important in FITC-sensitive ATP-binding site of P-type ATPases? A commentary to the state of the art.- Reinstatement of the ATP high energy paradigm.- Regulation of and intervention into the oxidative pentose phosphate pathway and adenine nucleotide metabolism in the heart.- The endogenous digitalis-like factor.- Functional antagonism by a monoclonal antibody to digoxin in a test system of cultured rat heart myocytes.- II: Ischemia-reperfusion and cardioprotection.- Biphasic changes in relaxation following reperfiision after myocardial ischemia.- Signal transduction in myocardial ischaemia and reperfusion.- Reversible and irreversible damage in reoxygenated 'ischemic' ventricular myocytes inculture.- Effects of hypoxia, simulated ischemia and reoxygenation on the contractile function of human atrial trabeculae.- The guanine nucleotide-binding regulatory proteins (G proteins) in myocardium with ischemia.- Role of reactive oxygen species in cardiovascular aging.- Uncoupling of mitochondrial oxidative phosphorylation alters lipid peroxidation-derived free radical production but not recovery of postischemic rat hearts and post-hypoxic endothelial cells.- Relationship between mechanical dysfunction and depression of sarcolemmal Ca2+-pump activity in hearts perfused with oxygen free radicals.- Relation between energy metabolism, glycolysis, noradrenaline release and duration of ischemia.- On the regulation of cellular energetics in health and disease.- Salvage of jeopardized myocardium by ischemic preconditioning: Is the quest over?.- Cytoprotective mechanisms in cultured cardiomyocytes.- Delayed cardioprotection is associated with the sub-cellular relocalisation of ventricular protein kinase C?, but not p42/44MAPK.- HSP25 in isolated perfused rat hearts: Localization and response to hyperthermia.- Molecular cloning, sequencing and expression analysis of a fatty acid transport gene in rat heart induced by ischemic preconditioning and oxidative stress.- Protaglandins and the antiarrhythmic effect of preconditioning in the isolated rat heart.- Prevention by 7-oxo-prostacyclin of the calcium paradox in rat heart: Role of the sarcolemmal (Na,K)-ATPase.- Donors of nitric oxide mimic effects of ischaemic preconditioning on reperfusion induced arrhythmias in isolated rat heart.- Crucial role of intracellular effectors on glycogenosis in the isolated rat heart: potential consequences on the myocardial tolerance to ischemia.- Probucol treatment reverses antioxidant and functional deficit in diabetic cardiomyopathy.- Glycogen phosphorylase isoenzyme BB in diagnosis of myocardial ischaemic injury and infarction.- Unaltered ryanodine receptor protein levels in ischemic cardiomyopathy.- Myocardial infarction and nitric oxide.- Estrogen effects in the heart.- Xenoreactive natural antibodies and induced antibodies - Their effects on beating cardiomyocytes as a model of a xenograft.- Index to Volumes 160 and 161.