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Abstract
The purpose of the search was to investigate the influence of feed additive “Butaselmevit-plus” on the biochemical indices of piglets blood when weaned. The experiments were conducted on the basis of Ltd. “KOSHET” of Mukachevo district, Transcarpathian region. Two groups of pigs were formed – control (C) and experimental (E), in the number of 10 individuals in each group, selected on the basis of analogues – age, breed and body weight. In the suckling period, pigletss were kept under sows in special machines, had constant access to the mother, and from 5 days of age – free access to concentrated feed. The research material was blood collected in the morning by puncture of the cranial vena cava on the 20th day of life (period before weaning), on the 25th day of life (period before weaning), on the 30th day of life (2 days after weaning), for 35 days of life (7 days after weaning), for 40 days of life (12 days after weaning). Weaning of piglets from sows at 28 days of age leads to a slight decrease in total protein and increased activity of aminotransferases. Increased activity of ALAT and ASAT in pigs' serum after weaning from sows reflects the nonspecific response of the organism to the action of stress factors and indicates an increased release of enzymes into the extracellular space. Feeding of piglets with feed additives “Butaselmevit-plus” promotes to enhance the protein synthesizing function of the liver and reduce the activity of aminotransferases. The decrease in the activity of aminotransferases in the blood of piglets of the experimental group, indicates that the components of the feed additive counteract the influence of stress, and also contribute to the maintenance the integrity of cell membranes specific to these organ enzymes, which prevents their output from the cells.
Highlights
Homeostasis of the animal's internal environment depends first and foremost on the interconnection of the individual units of the metabolic processes and the lability of the components, that participate in the common system (Ahmad et al, 2011; Petrukh et al, 2015)
The results of the search showed that the content of total protein in the serum of 20 daily piglets of the control and experimental groups ranged from 52.84 ± 1.20
The decrease in the activity of aminotransferases in the blood of piglets of the experimental group, indicates that the components of the feed additive counteract the effects of stress, and help to maintain the integrity of cell membranes specific to these organ enzymes, which prevents them from leaving the cells
Summary
Homeostasis of the animal's internal environment depends first and foremost on the interconnection of the individual units of the metabolic processes and the lability of the components, that participate in the common system (Ahmad et al, 2011; Petrukh et al, 2015). Blood as one of the body's biological fluids responds quantitatively and qualitatively to changes in its composition to any exogenous or endogenous influences, and it is a kind of biomarker that allows to determine the general state of organs and systems and to evaluate the course of major metabolic processes (Martyshuk et al, 2016; Lavryshyn et al, 2016; Chala & Rusak, 2016). New preparations and feed additives based on vegetable raw materials have been widely used in recent years to enhance the animal body's protective systems in the development of oxidative stress (Cherkashina & Petrenko, 2006; Skrypnyk, 2007; Saba еt al., 2010; Zhukova et al, 2016; Gutyj et al, 2017). Of particular importance is the search of the interaction of selenium with other trace elements, which are normalized in the rations, due to the increased techno-
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