Abstract

Human mouse and avian oviduct mucosa was studied histochemically and with light and electron microscope for the presence and localization of adenosine triphosphatases (ATPases); peritoneal fluid and serum were also studied. ATPase activity was found in oviductal fluid in all 3 species; no ATPase activity was found in sera and only very small amounts in peritoneal fluid. Light microscopy revealed ATPase-secreting cells most heavily concentrated in the lower preampulla of hens oviducts. ATPase secreting cells in human and mouse oviducts varied with age and hormonal states. Infant postmenopausal and follicular phase oviducts showed few active sites; oviducts from secretory phase oviducts had very high activity along the preampullar mucosal surface. Highest ATPase activity was demonstrated in and on the surface of secretory cells bordering the lumen.

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