Biochemical Changes in the Fertile and Sterile of Hydatid Cyst Fluid in Sheep

Abstract

Introduction: Hydatid cyst involves vital organs such as, liver, lungs, spleen, kidneys and so on. Hydatidosis could be seen in many ruminants and accidentally in human. Hydatidosis causes impairment physiological functions. This disease disturbs the balance of biochemical compounds. Material and methods: Eighty five livers and lungs from sheep having Hydatid cysts were taken from Ghaem Abattoir. Five milliliters of Hydatid fluid was taken from each from fertile and sterile cyst. Protein, cholesterol, glucose, phosphate, calcium and enzymes like alkaline phosphatase (ALP), lactate dehydrogenase (LDH), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) have been measured by Autoanalyzer apparatus. Flamphotometry has been used for Na and K measurement. Results: The mean of biochemical compound such as, protein, cholesterol, glucose and enzymes like ALP, LDH, ALT and AST was different in the fertile and sterile cysts of lung and liver in sheep. The total protein, cholesterol, glucose and LDH, ALP, AST enzymes differed significantly between fertile and sterile in liver.The above mentioned compounds of lung except cholesterol and alanine aminotransferase also differed significantly between sterile and fertile cysts. Mineral elements such as, Na+, K+, Ca2+ were different in fertile and sterile cysts in accordance to their location. Na, K and Ca in fertile cyst of liver were higher than sterile cyst. Conclusion: These results lead us to this idea that ability of the wall of sterile and fertile is different and this could be used as a hypothesis for biochemical control of Hydatidosis.