Abstract
Biological markers or biomarkers are the indicators of a particular biological state before the appearance of manifestations in form of a disease. A variety of blood biomarkers represent pathology of diabetes. Analysis of blood is an important technique for determining physiological and pathological condition. People suffering from Type 2 diabetes mellitus (T2DM) were part of the study. The people with bleeding disorders and those suffering from other diseases were not included in the study. There were more female (F) diabetic patients than male (M) patients. This case control observational study is an attempt to interpret data obtained from biochemical investigation of diagnostic biochemical parameters of complete blood count and lipid profile for their pathological implication and in prediction risk of Type 2 diabetes mellitus and related complications among the healthy subjects. Normality test was done to check for normal distribution of the data among females (1) and males (2) and the correlation test showed no significant relation of the of biochemical parameters with PBSS.
Highlights
Biomarkers “Biomarker or biological marker origin is the characteristic that is objectively measured and evaluated as an indicator of the normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention” (NIH Definition 2001).Biomarkers provide a dynamic and powerful approach to understand the spectrum of diseases
The study showed that there is an increase in the values of some biochemical parameters investigated in the Type 2 diabetes mellitus (T2DM) cases when compared to the control values but within the normal range
Gender specific of investigation of anemia is done in females when the hemoglobin levels are less than g/dL and in men when it is less than g/dL [32] (WHO recommended criteria)
Summary
Biomarkers “Biomarker or biological marker origin is the characteristic that is objectively measured and evaluated as an indicator of the normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention” (NIH Definition 2001).Biomarkers provide a dynamic and powerful approach to understand the spectrum of diseases. Among the non-genetic biomarkers the biochemical biomarkers are the independent predictors of Type 2 diabetes
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