Biochemical and physiological responses to metabolic stimuli in Friesian calves of differing genetic merit for milk production

Abstract

ABSTRACTChanges in blood metabolite and insulin concentrations in response to metabolic stimuli were evaluated as potential predictors of dairy merit. Calves of high or low genetic merit for milk production were subjected to the stress of: simulated feeds by injection of sodium propionate (0·5 mmol/kg body weight), a short fast and short-term cold exposure. Responses of insulin, free fatty acids, urea, glucose and D-β-hydroxybutyrate were determined by serial blood sampling.Injections of sodium propionate did not greatly affect blood metabolite concentrations but did sharply increase insulin concentrations; no difference in response between high and low lines was observed. During fasting serum free fatty acid and D-β-hydroxybutyrate concentrations were greatly increased but no variation due to line was observed. Urea concentrations were also greatly increased during fasting and in this case animals of high dairy merit showed a considerably smaller increase than animals of low dairy merit. Heart rates decreased by one-third during the fast but no variation due to line was apparent;during refeeding high dairy-merit animals had lower heart rates than low-merit animals.Short-term cold exposure did not significantly alter plasma insulin or metabolite concentrations.These results are discussed in relation to previous findings and it is concluded that serum urea concentrations during a fast may provide the basis for a useful and robust predictor of dairy merit in young animals.