Biochemical and nutritional markers and antioxidant activity in metabolic syndrome

Abstract

Abstract Background and objectives (1) Nutritional assessment of the diet followed by patients with metabolic syndrome and (2) biochemical analysis of the oxidation–reduction level in patients with metabolic syndrome. Materials and methods A cross-sectional study was conducted in patients with metabolic syndrome in Murcia. Fifty-three patients, 33 with and 20 without (control group) metabolic syndrome, were selected. The intervention consisted of completion of a recall survey and a test to nutritionally assess dietary intake. Anthropometric and laboratory variables, including those related to antioxidant activity, were also tested. Results Antioxidant activity was within normal limits in both groups (1.7 ± 0.2 mmol/L in the control group and 1.8 ± 0.1 mmol/L in the metabolic syndrome group) (NS). Superoxide dismutase levels were not significantly different between the groups. Mean glutathione reductase levels (U/L) were higher in the control group when compared to patients with metabolic syndrome ( p p Conclusions There is a trend to a poorer nutritional and biochemical profile in patients with metabolic syndrome, who also tend to have a greater degree of oxidative stress.